Article
Glutathione S-transferase polymorphisms and survival from head and neck cancer.
Head & neck - 1 Mar 2005
Geisler Stacy A, Olshan Andrew F, Cai Jianwen, Weissler Mark, Smith Joanna, Bell Douglas
Abstract excerpt
BACKGROUND: The purpose of this study was to evaluate the prognostic ability of polymorphisms of three genes involved in the metabolism of tobacco carcinogens (GSTT1, GSTM1, GSTP1) and one polymorphism of a DNA repair gene (XRCC1) for patients diagnosed with squamous cell carcinoma (SCC). METHODS: Cox proportional hazard models were used to estimate risk of death for a prospective cohort of 190 patients. RESULTS:...
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