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Article

High-throughput metabolic state analysis: the missing link in integrated functional genomics of yeasts.

The Biochemical journal - 1 Jun 2005

Villas-Bôas Silas G, Moxley Joel F, Akesson Mats, Stephanopoulos Gregory, Nielsen Jens

Abstract excerpt

The lack of comparable metabolic state assays severely limits understanding the metabolic changes caused by genetic or environmental perturbations. The present study reports the application of a novel derivatization method for metabolome analysis of yeast, coupled to data-mining software that achieve comparable throughput, effort and cost compared with DNA arrays. Our sample workup method enables simultaneous...

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Identifiers

PMID: 15667247
DOI: 10.1042/BJ20041162
PMCID: PMC1138975

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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