Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Construction of a metabolome library for transcription factor-related single gene mutants of Saccharomyces cerevisiae.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences - 1 Sept 2014

Hashim Zanariah, Teoh Shao Thing, Bamba Takeshi, Fukusaki Eiichiro

Abstract excerpt

Transcription factors (TFs) play an important role in gene regulation, providing control for cells to adapt to ever changing environments and different physiological states. Although great effort has been taken to study TFs through DNA-protein binding and microarray gene expression experiments, the understanding of transcriptional regulation is still lacking, due to lack of information that links TF regulatory...

Topics

Chromatography, High Pressure Liquid
Cluster Analysis
Databases, Factual
Gene Library
Metabolome
Mutation
Principal Component Analysis
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins
Tandem Mass Spectrometry

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Transcription Factors

Source

Identifiers

PMID: 24974314
DOI: 10.1016/j.jchromb.2014.05.041

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Construction of a metabolome library for transcription factor-related single gene mutants of Saccharomyces cerevisiae.PMID 24974314Read ↗

Comprehensive reanalysis of transcription factor knockout expression data in Saccharomyces cerevisiae reveals many new targets.Semantic proximity Read ↗

Functional discovery via a compendium of expression profiles.Semantic proximity Read ↗

High-throughput metabolic state analysis: the missing link in integrated functional genomics of yeasts.Semantic proximity Read ↗

Genomic and transcriptome analyses reveal that MAPK- and phosphatidylinositol-signaling pathways mediate tolerance to 5-hydroxymethyl-2-furaldehyde for industrial yeast Saccharomyces cerevisiae.Semantic proximity Read ↗

Pathway-based signature transcriptional profiles as tolerance phenotypes for the adapted industrial yeast Saccharomyces cerevisiae resistant to furfural and HMF.Semantic proximity Read ↗

Yeast adapts to diverse ecological niches driven by genomics and metabolic reprogrammingSemantic proximity Read ↗

Cell Lysate Microarray for Mapping the Network of Genetic Regulators for Histone Marks.Semantic proximity Read ↗

Toward a global analysis of metabolites in regulatory mutants of yeast.Semantic proximity Read ↗

Metabolic, Organoleptic and Transcriptomic Impact of Saccharomyces cerevisiae Genes Involved in the Biosynthesis of Linear and Substituted Esters.Semantic proximity Read ↗

Comprehensive phenotypic analysis of single-gene deletion and overexpression strains of Saccharomyces cerevisiae.Semantic proximity Read ↗

A functional genomics strategy that uses metabolome data to reveal the phenotype of silent mutations.Semantic proximity Read ↗

Tolerant industrial yeast Saccharomyces cerevisiae posses a more robust cell wall integrity signaling pathway against 2-furaldehyde and 5-(hydroxymethyl)-2-furaldehyde.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.