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Article

A novel platform for automated high-throughput fluxome profiling of metabolic variants.

Metabolic engineering - 1 Sept 2014

Heux Stéphanie, Poinot Juliette, Massou Stéphane, Sokol Serguei, Portais Jean-Charles

Abstract excerpt

Advances in metabolic engineering are enabling the creation of a large number of cell factories. However, high-throughput platforms do not yet exist for rapidly analyzing the metabolic network of the engineered cells. To fill the gap, we developed an integrated solution for fluxome profiling of large sets of biological systems and conditions. This platform combines a robotic system for (13)C-labelling experiments...

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PMID: 24930895
DOI: 10.1016/j.ymben.2014.06.001

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