Article
Caenorhabditis elegans mutants resistant to inhibitors of acetylcholinesterase.
Genetics - 1 Jun 1995
Nguyen M, Alfonso A, Johnson C D, Rand J B
Abstract excerpt
We characterized 18 genes from Caenorhabditis elegans that, when mutated, confer recessive resistance to inhibitors of acetylcholinesterase. These include previously described genes as well as newly identified genes; they encode essential as well as nonessential functions. In the absence of acetylcholinesterase inhibitors, the different mutants display a wide range of behavioral deficits, from mild uncoordination...
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