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Article

The relative power of family-based and case-control designs for linkage disequilibrium studies of complex human diseases. II. Individual genotyping.

Genome research - 1 Mar 1999

Teng J, Risch N

Abstract excerpt

In this paper we consider test statistics based on individual genotyping. For sibships without parents, but with unaffected as well as affected sibs, we introduce a new test statistic (referred to as TDS), which contrasts the allele frequency in affected sibs versus that estimated for the parents from the entire sibship. For sibships without parents, this test is analogous to the TDT and is completely robust to...

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PMID: 10077529

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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