Article
The relative power of family-based and case-control designs for linkage disequilibrium studies of complex human diseases. II. Individual genotyping.
Genome research - 1 Mar 1999
Teng J, Risch N
Abstract excerpt
In this paper we consider test statistics based on individual genotyping. For sibships without parents, but with unaffected as well as affected sibs, we introduce a new test statistic (referred to as TDS), which contrasts the allele frequency in affected sibs versus that estimated for the parents...
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