Article
Allele and genotype frequencies of cytochrome P450 2B6 gene in a Mongolian population.
Drug metabolism and disposition: the biological fate of chemicals - 1 Oct 2009
Davaalkham Jagdagsuren, Hayashida Tsunefusa, Tsuchiya Kiyoto, Gatanaga Hiroyuki, Nyamkhuu Dulmaa, Oka Shinichi
Abstract excerpt
CYP2B6 plays an important role in metabolizing various drugs in common clinical use. Increasing interest in CYP2B6 genetic polymorphism was stimulated by revelations of a specific CYP2B6 genotype significantly affecting the metabolism of efavirenz, an anti-HIV type-1 agent. The present study determined the CYP2B6 haplotype in 100 healthy unrelated Mongolian volunteers by analyzing the genotypes of nine single...
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