Article
Genetic variants in CYP (-1A2, -2C9, -2C19, -3A4 and -3A5), VKORC1 and ABCB1 genes in a black South African population: a window into diversity.
Pharmacogenomics - 1 Dec 2011
Dandara Collet, Lombard Zané, Du Plooy Ingrid, McLellan Tracy, Norris Shane A, Ramsay Michèle
Abstract excerpt
AIM: The frequencies of variants of pharmacogenetic importance differ across populations. African populations exhibit the greatest genetic heterogeneity, cautioning against extrapolating results among African groups. The aim of this study was to genotype pharmacogenetically relevant variants in black South Africans, to expand the limited data set available for indigenous African populations. SUBJECTS & METHODS: A...
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