Article
Getting to Know Viral Evolutionary Strategies: Towards the Next Generation of Quasispecies Models.
Current topics in microbiology and immunology - 1 Jan 2016
Manrubia Susanna, Lázaro Ester
Abstract excerpt
Viral populations are formed by complex ensembles of genomes with broad phenotypic diversity. The adaptive strategies deployed by these ensembles are multiple and often cannot be predicted a priori. Our understanding of viral dynamics is mostly based on two kinds of empirical approaches: one directed towards characterizing molecular changes underlying fitness changes and another focused on population-level...
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