Article
Expression and Functional Analysis of the Subtilin Immunity Genes <i>spaIFEG</i> in the Subtilin-Sensitive Host <i>Bacillus subtilis</i> MO1099
19 Jan 2005
Abstract excerpt
Bacillus subtilis ATCC 6633 produces the cationic pore-forming lantibiotic subtilin, which preferentially acts on gram-positive microorganisms; self protection of the producer cells is mediated by the four genes spaIFEG. To elucidate the mechanism of subtilin autoimmunity, we transferred different combinations of subtilin immunity genes under the control of an inducible promoter into the genome of...
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