Article
Biosynthesis of the lantibiotic subtilin is regulated by a histidine kinase/response regulator system.
Applied and environmental microbiology - 1 Jan 1993
Klein C, Kaletta C, Entian K D
Abstract excerpt
Subtilin is a lanthionine-containing peptide antibiotic (lantibiotic) which is produced by Bacillus subtilis ATCC 6633. Upstream from the structural gene of subtilin, spaS, three genes (spaB, spaT, and spaC) which are involved in the biosynthesis of subtilin have been identified (C. Klein, C. Kal...
Topics
- Amino Acid Sequence
- Anti-Bacterial Agents
- Bacillus subtilis
- Bacterial Proteins
- Bacteriocins
- Base Sequence
- Gene Deletion
- Gene Expression Regulation, Bacterial
- Genes, Bacterial
- Histidine Kinase
- Molecular Sequence Data
- Mutation
- Peptides
- Peptides, Cyclic
- Phenotype
- Protein Kinases
- Sequence Homology, Amino Acid
- Signal Transduction