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The requirement for the amino acid co-germinant during <i>C. difficile</i> spore germination is influenced by mutations in <i>yabG</i> and <i>cspA</i>

2018-09-26

Abstract excerpt

Clostridium difficile spore germination is critical for the transmission of disease. C. difficile spores germinate in response to cholic acid derivatives, such as taurocholate (TA), and amino acids, such as glycine or alanine. Although the bile acid germinant receptor is known, the amino acid germinant receptor has remained elusive. Here, we used EMS mutagenesis to generate mutants with altered requirements for t...

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Literature Corpus work
6eca8ece-ff56-5232-85d9-84ca848baa48
DOI
10.1101/427021
Open publication

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The requirement for the amino acid co-germinant during <i>C. difficile</i> spore germination is influenced by mutations in <i>yabG</i> and <i>cspA</i>DOI 10.1101/427021
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