Article
The InhA metalloproteases of Bacillus cereus contribute concomitantly to virulence.
Journal of bacteriology - 1 Jan 2010
Guillemet Elisabeth, Cadot Céline, Tran Seav-Ly, Guinebretière Marie-Hélène, Lereclus Didier, Ramarao Nalini
Abstract excerpt
The virulence of Bacillus cereus requires that bacteria have the capacity to colonize their host, degrade specific tissues, and circumvent the host immune system. To study this aspect of pathogenesis, we focused on three metalloproteases, InhA1, InhA2, and InhA3, which share more than 66% identity. The expression of these metalloprotease genes was assessed by transcriptional fusions with a lacZ reporter gene. The...
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