Article
A three-protein signaling pathway governing immunity to a bacterial cannibalism toxin.
Cell - 10 Feb 2006
Ellermeier Craig D, Hobbs Errett C, Gonzalez-Pastor Jose E, Losick Richard
Abstract excerpt
We describe a three-protein signal-transduction pathway that governs immunity to a protein toxin involved in cannibalism by the spore-forming bacterium Bacillus subtilis. Cells of B. subtilis enter the pathway to sporulate under conditions of nutrient limitation but delay becoming committed to spore formation by killing nonsporulating siblings and feeding on the dead cells. Killing is mediated by the exported...
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