Article
Mtreemix: a software package for learning and using mixture models of mutagenetic trees.
Bioinformatics (Oxford, England) - 1 May 2005
Beerenwinkel Niko, Rahnenführer Jörg, Kaiser Rolf, Hoffmann Daniel, Selbig Joachim, Lengauer Thomas
Abstract excerpt
SUMMARY: Mixture models of mutagenetic trees constitute a class of probabilistic models for describing evolutionary processes that are characterized by the accumulation of permanent genetic changes. They have been applied to model the accumulation of chromosomal gains and losses in tumor development and the development of drug resistance-associated mutations in the HIV genome.Mtreemix is a software package for...
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