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Article

A novel T cell receptor transgenic animal model of seborrheic dermatitis-like skin disease.

The Journal of investigative dermatology - 1 Jan 2005

Oble Darryl A, Collett Elisabeth, Hsieh Mindy, Ambjørn Malene, Law Jennie, Dutz Jan, Teh Hung-Sia

Abstract excerpt

We have characterized a novel animal model of the common inflammatory skin disease seborrheic dermatitis (SD) that involves the expression of the self-specific 2C transgenic T cell receptor on the DBA/2 genetic background. Opportunistic fungal pathogens are present in the primary histological lesions and severe disease can be mitigated by the administration of fluconazole, demonstrating a role for infection in...

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PMID: 15654969
DOI: 10.1111/j.0022-202X.2004.23565.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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