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Immunology and pathogenesis of canine demodicosis

9 Jun 2014

Abstract excerpt

Demodex mites colonized the hair follicles and sebaceous glands of mammals millions of years ago and have remained relatively unchanged in this protected ecologic niche since then. The host immune system detects and tolerates their presence. Toll-like receptor-2 of keratinocytes has been demonstrated to recognize mite chitin and to elicit an innate immune response. The subsequent acquired immune response is...

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PMID: 24910252
DOI: 10.1111/vde.12136

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