Article
Alopecia areata - animal models.
Clinical and experimental dermatology - 1 Jul 2002
McElwee K J, Hoffmann R
Abstract excerpt
Several rodent models with spontaneous and induced alopecia areata (AA), a nonscarring inflammatory hair loss disease with suspected autoimmune elements, have been identified. Of these, the C3H/HeJ mouse and DEBR rat have been most extensively used in examining AA development. Flow cytometry and micro array characterization, manipulation of inflammatory cells by in vivo cell depletion or cell receptor blockade,...
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