Article
Variants of CARD15 are associated with an aggressive clinical course of Crohn's disease--an IG-IBD study.
The American journal of gastroenterology - 1 Jan 2005
Annese Vito, Lombardi Giovanni, Perri Francesco, D'Incà Renata, Ardizzone Sandro, Riegler Gabriele, Giaccari Stelio, Vecchi Maurizio, Castiglione Fabiana, Gionchetti Paolo, Cocchiara Elena, Vigneri Sergio, Latiano Anna, Palmieri Orazio, Andriulli Angelo
Abstract excerpt
BACKGROUND: Three major variants of the CARD15 gene confer susceptibility to Crohn's disease (CD). Whether or not these variants correlate with specific clinical features of the disease is under evaluation. AIM: We investigated the possible association of CARD15 variants with specific clinical characteristics, including the occurrence of anti-Saccharomyces cerevisiae antibodies (ASCA) and antineutrophil...
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