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Article

Diverse effects of the CARD15 and IBD5 loci on clinical phenotype in 630 patients with Crohn's disease.

European journal of gastroenterology & hepatology - 1 Jan 2008

Onnie Clive M, Fisher Sheila A, Prescott Natalie J, Mirza Muddassar M, Green Peter, Sanderson Jeremy, Forbes Alastair, Lewis Cathryn M, Mathew Christopher G

Abstract excerpt

OBJECTIVES: Genetic variants at the CARD15 and IBD5 loci are strongly associated with Crohn's disease (CD), but evidence of the effect of these variants on the clinical expression of CD is conflicting and has often been hampered by small sample sizes. We studied 630 well-characterized patients to clarify the genotype/phenotype relationship in CD. METHODS: Patients and healthy controls were genotyped for three...

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Age of Onset
Crohn Disease
Gene Frequency
Granuloma
Linkage Disequilibrium

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Nod2 Signaling Adaptor Protein

Postoperative Complications

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PMID: 18090989
DOI: 10.1097/MEG.0b013e3282f1622b

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