Article
Contribution of CARD15 variants in determining susceptibility to Crohn's disease in Sweden.
Scandinavian journal of gastroenterology - 1 Jun 2006
Törkvist Leif, Noble Colin L, Lördal Mikael, Sjöqvist Urban, Lindforss Ulrik, Nimmo Elaine R, Russell Richard K, Löfberg Robert, Satsangi Jack
Abstract excerpt
OBJECTIVE: Crohn's disease (CD) is a chronic inflammatory bowel disorder caused by environmental and genetic factors. Mutations in the CARD15 gene have been associated with CD. No previous case-control CARD15 study has been performed in the Swedish population. MATERIAL AND METHODS: The study comprised of 321 individuals: 178 with CD and 143 healthy controls (HCs), all from Stockholm County. All were genotyped for...
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