Article
NOD2/CARD15 in healthy relatives of IBD patients.
European review for medical and pharmacological sciences - 1 Jan 2000
Annese V, Latiano A, Palmieri O, Lombardi G, Andriulli A
Abstract excerpt
BACKGROUND: Crohn's disease (CD) and Ulcerative Colitis (UC) are related chronic inflammatory disorders of the intestine (IBD) caused by a combination of genetic and environmental factors. Three polymorphisms within the NOD2/CARD15 gene are highly associated with CD, increasing the risk from 2 up to 44-fold, depending on the presence of one or two risk alleles. Aim of this study was to investigate the presence of...
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