Article
Calpain-10 gene polymorphisms and risk of type 2 diabetes mellitus in Mexican mestizos.
Genetics and molecular research : GMR - 27 Mar 2015
Picos-Cárdenas V J, Sáinz-González E, Miliar-García A, Romero-Zazueta A, Quintero-Osuna R, Leal-Ugarte E, Peralta-Leal V, Meza-Espinoza J P
Abstract excerpt
The calpain-10 gene is expressed primarily in tissues important in glucose metabolism; thus, some of its polymorphisms have been associated with type 2 diabetes. In this study, we examined the association between the calpain-10 single-nucleotide polymorphism (SNP)-43, SNP-19, and SNP-63 and type 2 diabetes in Mexican mestizos. We included 211 patients and 152 non-diabetic subjects. Polymerase chain reaction was...
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