Article
Phenotypic-genotypic analysis of CYP2C19 in the Jewish Israeli population.
Clinical pharmacology and therapeutics - 1 Mar 1999
Sviri S, Shpizen S, Leitersdorf E, Levy M, Caraco Y
Abstract excerpt
OBJECTIVES: Evaluation of CYP2C19 activity and the frequency of CYP2C19 alleles in the Jewish Israeli population. METHODS: One hundred forty Jewish Israeli subjects received 100 mg racemic mephenytoin and collected urine for 8 hours. Urinary concentrations of mephenytoin enantiomers and 4'-hydrox...
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