Article
[Antigenic activity of delta-antigen peptides corresponding to three genotypes of the delta hepatitis virus].
Voprosy virusologii - 1 Jan 2000
Dement'eva E V, Kruglov I V, Pimenov V K, Semiletov Iu A
Abstract excerpt
Six synthetic peptides from immunodominant region 65-80 aa derived from the sequences of delta-antigen corresponding to 3 HDV genotypes were obtained. Their antigenic activities were assessed by indirect enzyme immunoassay with sera of patients with hepatitis D and of asymptomatic carriers of anti-delta antibodies. Differences in antigenic characteristics of full-size 65-80 and truncated 71-80 aa peptides...
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