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Article

Immunohistochemical analysis of thyroid‐specific transcription factors in thyroid tumors

12 Apr 2006

Abstract excerpt

Thyroid transcription factor 1 (TTF1), thyroid transcription factor 2 (TTF2) and paired box gene 8 (Pax8) are demonstrated to play a crucial role for the differentiation and organogenesis of thyroid follicular cells. Their roles in thyroid carcinogenesis are not very clear. Because dedifferentiation is a common process in thyroid carcinogenesis, thyroid-specific transcription factors seem also to be involving in...

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PMID: 16669872
DOI: 10.1111/j.1440-1827.2006.01959.x

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