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Article

Alteration of p73 in pediatric de novo acute lymphoblastic leukemia.

Biochemical and biophysical research communications - 18 Feb 2005

Sahu Geeta Ram, Das Bibhu Ranjan

Abstract excerpt

The frequency of p73 mutation is low in hematologic malignancies as well as solid tumors. Aberrant DNA methylation of multiple promoter associated CpG islands is a frequent phenomenon in acute lymphoblastic leukemia (ALL). In the present study, we scanned for mutations in the exons 4, 5, 6, and 7 of p73 gene. Using PCR-based methylation analysis, we have explored the prevalence of methylation of this pathway in a...

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Identifiers

PMID: 15649410
DOI: 10.1016/j.bbrc.2004.12.064

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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