Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Aberrant DNA methylation in pediatric patients with acute lymphocytic leukemia

23 Jan 2003

Abstract excerpt

BACKGROUND: Aberrant methylation of promoter-associated cystosine-guanine (CpG) islands is an epigenetic modification of DNA frequently observed in adult patients with acute lymphocytic leukemia (ALL). This epigenetic modification has been associated with gene silencing, malignant transformation, and aging. It is not known whether there are epigenetic differences between pediatric patients and adult patients with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Lymphoblastic Leukemia research
Share to Childhood Cancer Survivors' Quality of Life
Share to Epigenetics and DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 12548613
DOI: 10.1002/cncr.11090

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Aberrant DNA methylation in pediatric patients with acute lymphocytic leukemiaPMID 12548613Read ↗

Epigenetics in pediatric acute lymphoblastic leukemiaSemantic proximity Read ↗

A Comprehensive Overview of Recent Advances in Epigenetics in Pediatric Acute Lymphoblastic LeukemiaSemantic proximity Read ↗

Epigenetic Modifications in Pediatric Acute Lymphoblastic LeukemiaSemantic proximity Read ↗

Genome-wide signatures of differential DNA methylation in pediatric acute lymphoblastic leukemiaSemantic proximity Read ↗

Aberrant p15 promoter methylation in adult and childhood acute leukemias of nearly all morphologic subtypes: potential prognostic implicationsSemantic proximity Read ↗

Clinical significance of aberrant DNA methylation in childhood acute lymphoblastic leukemiaSemantic proximity Read ↗

Alteration of p73 in pediatric de novo acute lymphoblastic leukemia.Semantic proximity Read ↗

Poor prognosis in acute lymphoblastic leukemia may relate to promoter hypermethylation of cancer-related genesSemantic proximity Read ↗

Concurrent methylation of multiple genes in childhood ALL: Correlation with phenotype and molecular subgroup.Semantic proximity Read ↗

Promoter methylation and expression levels of selected hematopoietic genes in pediatric B-cell acute lymphoblastic leukemiaSemantic proximity Read ↗

DNA methylation pattern is altered in childhood T-cell acute lymphoblastic leukemia patients as compared with normal thymic subsets: insights into CpG island methylator phenotype in T-ALLSemantic proximity Read ↗

Genomic profiling of adult acute lymphoblastic leukemia by single nucleotide polymorphism oligonucleotide microarray and comparison to pediatric acute lymphoblastic leukemia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.