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Article

Loss of p73 gene expression in leukemias/lymphomas due to hypermethylation.

1 Aug 1999

Abstract excerpt

The p73 gene, a member of the p53 family, is a new candidate tumor suppressor gene. To investigate the possibility of genetic alteration of p73 in leukemia and lymphoma, we examined 55 cell lines and 39 patient samples together with 17 nonhematopoietic cancer cell lines. Gene expression of p73 was detected by reverse transcriptase-polymerase chain reaction (RT-PCR) in cell lines (5 of 7 pre B/B-acute...

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PMID: 10419905
DOI: 10.1182/blood.v94.3.1113.415k33_1113_1120

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Loss of p73 gene expression in leukemias/lymphomas due to hypermethylation.PMID 10419905Read ↗

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