Article
Clinical and virological characteristics of lamivudine resistance in chronic hepatitis B patients: a single center experience.
Journal of medical virology - 1 Mar 2005
Sun Jian, Wang Zhanhui, Ma Shiwu, Zeng Guobing, Zhou Zhiyong, Luo Kangxian, Hou Jinlin
Abstract excerpt
We have investigated the characteristics of lamivudine-resistant strains in patients with chronic hepatitis B in Guangdong, China, where the predominant genotypes are B and C. Two hundred forty-seven patients treated with lamivudine in Nanfang Hospital were followed-up. Patients with hepatitis B e antigen (HBeAg) positive and hepatitis B virus (HBV)-DNA levels over 7.5 x 10(6) copies/ml at baseline had a shorter...
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