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Article

Low rate of YMDD motif mutations in polymerase gene of hepatitis B virus in chronically infected patients not treated with lamivudine.

Journal of gastroenterology - 1 Jan 2004

Matsuda Marie, Suzuki Fumitaka, Suzuki Yoshiyuki, Tsubota Akihito, Akuta Norio, Hosaka Tetsuya, Someya Takashi, Kobayashi Masahiro, Saitoh Satoshi, Arase Yasuji, Satoh Junko, Takagi Kimiko, Kobayashi Mariko, Ikeda Kenji, Kumada Hiromitsu

Abstract excerpt

BACKGROUND: Lamivudine is used for the treatment of chronic hepatitis B (CH-B), and exhibits excellent antiviral activity. However, longterm administration increases the likelihood of the emergence of resistant viruses, with an accompanying relapse of hepatitis. However, recent studies have repor...

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Source

Identifiers

PMID: 14767732
DOI: 10.1007/s00535-003-1242-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14767732-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

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Low rate of YMDD motif mutations in polymerase gene of hepatitis B virus in chronically infected patients not treated with lamivudine.PMID 14767732Read ↗

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Emergence of a novel lamivudine-resistant hepatitis B virus variant with a substitution outside the YMDD motif.Semantic proximity Read ↗

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