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Article

Effect of CYP1A1 gene polymorphisms on estrogen metabolism and bone density.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Feb 2005

Napoli Nicola, Villareal Dennis T, Mumm Steven, Halstead Linda, Sheikh Sharmin, Cagaanan Manuel, Rini Giovam Battista, Armamento-Villareal Reina

Abstract excerpt

UNLABELLED: In this study, we evaluated the effect of polymorphisms of the CYP1A1 gene, linked to hormone-related cancers, on estrogen metabolism and BMD. We found that variants carrying the A allele (CA and AA) for the C4887A polymorphism have a significantly higher degree of estrogen catabolism and lower femoral BMD. INTRODUCTION: Polymorphisms of the CYP1A1 gene, one of the key enzymes that metabolize...

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Source

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Identifiers

PMID: 15647817
DOI: 10.1359/JBMR.041110
PMCID: PMC9036542

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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