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Article

The Val432Leu polymorphism of the CYP1B1 gene is associated with differences in estrogen metabolism and bone density.

Bone - 1 Mar 2009

Napoli Nicola, Rini Giovam Battista, Serber Daniel, Giri Tusar, Yarramaneni Jayasree, Bucchieri Salvatore, Camarda Lawrence, Di Fede Gaetana, Camarda Marcello Rosolino, Jain Sudahansu, Mumm Steven, Armamento-Villareal Reina

Abstract excerpt

Polymorphisms of the CYP450 genes that encode for the enzymes that metabolize estrogen are linked to hormone-related cancers. We investigated the impact of two polymorphisms of the CYP1B1 gene previously reported to be associated with hormone-related disorders on estrogen metabolism and bone mineral density (BMD), another hormone-dependent condition, in women from different ethnic backgrounds. Four hundred...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18977467
DOI: 10.1016/j.bone.2008.09.018
PMCID: PMC3966713

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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