Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Oocyte-based screening system for anti-microtubule agents.

The Journal of reproduction and development - 1 Dec 2004

Shin Deug-Young, Choi Tae-Saeng

Abstract excerpt

Taxol and vinblastine have been widely used in cancer chemotherapy as anti-microtubule agents. However, there are on-going efforts to find new anti-microtubule agents with fewer of the side effects associated with these drugs, such as toxicity or the development of resistance. The standard method used to identify anti-microtubule agents has been the in vitro microtubule polymerization assay. One limitation of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antineoplastic Agents, Phytogenic
Share to Drug Screening Assays, Antitumor
Share to Metaphase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Methanol

Share to Mice, Inbred ICR

Share to Paclitaxel

Share to Tubulin

Share to Vinblastine

Source

Identifiers

PMID: 15647616
DOI: 10.1262/jrd.50.647

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Oocyte-based screening system for anti-microtubule agents.PMID 15647616Read ↗

How Do Microtubule-Targeted Drugs Work? An OverviewSemantic proximity Read ↗

Microtubule inhibitors: Differentiating tubulin-inhibiting agents based on mechanisms of action, clinical activity, and resistanceSemantic proximity Read ↗

Microtubules and Cell Division: Potential Pharmacological Targets in Cancer TherapySemantic proximity Read ↗

Targeting Microtubules for Cancer ChemotherapySemantic proximity Read ↗

A review of research progress of antitumor drugs based on tubulin targetsSemantic proximity Read ↗

Microtubules: A dynamic target in cancer therapySemantic proximity Read ↗

Targeting Microtubules by Natural Agents for Cancer TherapySemantic proximity Read ↗

Anti-mitotic agents: Are they emerging molecules for cancer treatment?Semantic proximity Read ↗

Microtubule-Targeting Drugs: More than AntimitoticsSemantic proximity Read ↗

Microtubule Active Agents: Beyond the Taxane FrontierSemantic proximity Read ↗

Mitotic drug targetsSemantic proximity Read ↗

New Microtubule / Tubulin-Targeted Anticancer Drugs and Novel Chemotherapeutic StrategiesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.