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Article

p27Kip1 acts downstream of N-cadherin-mediated cell adhesion to promote myogenesis beyond cell cycle regulation.

Molecular biology of the cell - 1 Mar 2005

Messina Graziella, Blasi Cristiana, La Rocca Severina Anna, Pompili Monica, Calconi Attilio, Grossi Milena

Abstract excerpt

It is widely acknowledged that cultured myoblasts can not differentiate at very low density. Here we analyzed the mechanism through which cell density influences myogenic differentiation in vitro. By comparing the behavior of C2C12 myoblasts at opposite cell densities, we found that, when cells are sparse, failure to undergo terminal differentiation is independent from cell cycle control and reflects the lack of...

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Identifiers

PMID: 15647380
DOI: 10.1091/mbc.e04-07-0612
PMCID: PMC551508

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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