Article
An siRNA-based screen in C2C12 myoblasts identifies novel genes involved in myogenic differentiation.
Experimental cell research - 1 Oct 2017
Alwan Rayan, Bruel Ange-Line, Da Silva Anne, Blanquet Véronique, Bouhouche Khaled
Abstract excerpt
Myogenesis is a highly regulated multi-step process involving myoblast proliferation and differentiation. Although studies over the last decades have identified several factors governing these distinct major phases, many of them are not yet known. In order to identify novel genes, we took advantage of the C2C12 myoblastic line to establish a functional siRNA screen combined with quantitative-imaging analysis of a...
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