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Article

Reduced differentiation potential of primary MyoD-/- myogenic cells derived from adult skeletal muscle.

The Journal of cell biology - 22 Feb 1999

Sabourin L A, Girgis-Gabardo A, Seale P, Asakura A, Rudnicki M A

Abstract excerpt

To gain insight into the regeneration deficit of MyoD-/- muscle, we investigated the growth and differentiation of cultured MyoD-/- myogenic cells. Primary MyoD-/- myogenic cells exhibited a stellate morphology distinct from the compact morphology of wild-type myoblasts, and expressed c-met, a receptor tyrosine kinase expressed in satellite cells. However, MyoD-/- myogenic cells did not express desmin, an...

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Identifiers

PMID: 10037786
DOI: 10.1083/jcb.144.4.631
PMCID: PMC2132931

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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