Article
B cells promote tumor progression in a mouse model of HPV-mediated cervical cancer.
International journal of cancer - 15 Sept 2016
Tang Alexandre, Dadaglio Gilles, Oberkampf Marine, Di Carlo Selene, Peduto Lucie, Laubreton Daphné, Desrues Belinda, Sun Cheng-Ming, Montagutelli Xavier, Leclerc Claude
Abstract excerpt
Enhancing anti-tumor immunity and preventing tumor escape are efficient strategies to increase the efficacy of therapeutic cancer vaccines. However, the treatment of advanced tumors remains difficult, mainly due to the immunosuppressive tumor microenvironment. Regulatory T cells and myeloid-derived suppressor cells have been extensively studied, and their role in suppressing tumor immunity is now well...
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