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Article

TORC1 and TORC2 converge to regulate the SAGA co-activator in response to nutrient availability.

EMBO reports - 1 Dec 2017

Laboucarié Thomas, Detilleux Dylane, Rodriguez-Mias Ricard A, Faux Céline, Romeo Yves, Franz-Wachtel Mirita, Krug Karsten, Maček Boris, Villén Judit, Petersen Janni, Helmlinger Dominique

Abstract excerpt

Gene expression regulation is essential for cells to adapt to changes in their environment. Co-activator complexes have well-established roles in transcriptional regulation, but less is known about how they sense and respond to signaling cues. We have previously shown that, in fission yeast, one such co-activator, the SAGA complex, controls gene expression and the switch from proliferation to differentiation in...

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Identifiers

PMID: 29079657
DOI: 10.15252/embr.201744942
PMCID: PMC5709762

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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