Article
The TSC/Rheb/TOR signaling pathway in fission yeast and mammalian cells: temperature sensitive and constitutive active mutants of TOR.
Cell cycle (Georgetown, Tex.) - 15 Jul 2007
Aspuria Paul-Joseph, Sato Tatsuhiro, Tamanoi Fuyuhiko
Abstract excerpt
The TSC/Rheb/TOR signaling pathway plays important roles in growth and cell cycle regulation. The main player TOR belongs to the PI3K-related protein kinase family. Recent studies utilizing fission yeast Tor2 have led to the identification of a number of amino acid changes that lead to inactivati...
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