Article
Structural variants in the retinoid receptor genes in patients with schizophrenia and other psychiatric diseases.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Feb 2005
Feng Jinong, Chen Jiesheng, Yan Jin, Jones Ian R, Craddock Nick, Cook Edwin H, Goldman David, Heston Leonard L, Sommer Steve S
Abstract excerpt
Retinoid receptors (RARs and RXRs) regulate brain morphogenesis and function. Defects in these receptors may contribute to schizophrenia or other psychiatric diseases. To test the hypothesis that genetic variants of the retinoid receptor genes may predispose to schizophrenia and other psychiatric diseases, the six RAR and RXR genes and a heterodimer partner, the NURR1 gene, were scanned in 100 schizophrenia...
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