Article
Scanning of estrogen receptor alpha (ERalpha) and thyroid hormone receptor alpha (TRalpha) genes in patients with psychiatric diseases: four missense mutations identified in ERalpha gene.
American journal of medical genetics - 8 May 2001
Feng J, Yan J, Michaud S, Craddock N, Jones I R, Cook E H, Goldman D, Heston L L, Peltonen L, Delisi L E, Sommer S S
Abstract excerpt
Estrogen and thyroid hormones exert effects on growth, development, and differentiation of the nervous system. Hormone administration can lead to changes in behavior, suggesting that genetic variants of the estrogen receptor alpha (ERalpha) and the thyroid hormone receptor alpha (TRalpha) genes may predispose to psychiatric diseases. To investigate this possibility, regions of likely functional significance (all...
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