Article
NR4A2 and schizophrenia: lack of association in a Portuguese/Brazilian study.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jul 2004
Ruano Dina, Macedo António, Dourado Ana, Soares Maria João, Valente José, Coelho Isabel, Santos Vítor, Azevedo Maria Helena, Goodman Ann, Hutz Mara Helena, Gama Clarissa, Lobato Maria Inês, Belmonte-de-Abreu Paulo, Palha Joana Almeida
Abstract excerpt
The present study investigates the association of mutations in the nuclear receptor NR4A2 in schizophrenic patients. The human Nur-related receptor 1, NR4A2, is an orphan nuclear receptor that can be constitutively active as a transcription factor and for which no natural ligand has yet been iden...
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