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Retinoic acid-related orphan receptor alpha (RORA) variants are associated with autism spectrum disorder.

Metabolic brain disease - 1 Oct 2017

Sayad Arezou, Noroozi Rezvan, Omrani Mir Davood, Taheri Mohammad, Ghafouri-Fard Soudeh

Abstract excerpt

Autism spectrum disorder (ASD) is a neurodevelopmental disorder with various epidemiologic, genetic, epigenetic, and environmental factors being associated with it. The observed sex bias in ASD towards male has prompted investigators to propose sex-dependent mechanisms for ASD. Retinoic acid-related orphan receptor-alpha (RORA) is a new autism candidate gene that has been shown to be differentially regulated by...

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Identifiers

PMID: 28608249
DOI: 10.1007/s11011-017-0049-6

Genes

RORA

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