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Article

The yeast endosomal Na+K+/H+ exchanger Nhx1 regulates cellular pH to control vesicle trafficking.

Molecular biology of the cell - 1 Mar 2005

Brett Christopher L, Tukaye Deepali N, Mukherjee Sanchita, Rao Rajini

Abstract excerpt

The relationship between endosomal pH and function is well documented in viral entry, endosomal maturation, receptor recycling, and vesicle targeting within the endocytic pathway. However, specific molecular mechanisms that either sense or regulate luminal pH to mediate these processes have not been identified. Herein we describe the use of novel, compartment-specific pH indicators to demonstrate that yeast Nhx1,...

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Identifiers

PMID: 15635088
DOI: 10.1091/mbc.e04-11-0999
PMCID: PMC551501

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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