Article

The Na <sup>+</sup> (K <sup>+</sup> )/H <sup>+</sup> exchanger Nhx1 controls multivesicular body-vacuolar lysosome fusion

2017-07-29

Abstract excerpt

<h4>ABSTRACT</h4> Loss-of-function mutations in human endosomal Na + (K + )/H + Exchangers (NHEs) NHE6 and NHE9 are implicated in neurological disorders including Christianson Syndrome, autism and attention deficit and hyperactivity disorder (ADHD). These mutations disrupt retention of surface receptors within neurons and glial cells by affecting their delivery to lysosomes for degradation. However, the molecu...

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Literature Corpus work: d2d6c93b-2525-550e-afe2-ef20cc2d2407
DOI: 10.1101/170175

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