Article
Expression and function of Slit1alpha, a novel alternative splicing product for slit1.
Journal of biochemistry - 1 Nov 2004
Tanno Toshihiko, Takenaka Shigeo, Tsuyama Shingo
Abstract excerpt
Slits are large molecular and extracellular glycoproteins that may function as chemorepellents in axon guidance and neural cell migration. The heterogeneity of the mRNA for slit has been described. Its variants indicate considerable potential for alternative splicing, resulting in the generation of multiple protein isoforms. We examined the regions in which these isoforms are expressed, and identified the highest...
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