Article
Expression of Trps1 during mouse embryonic development.
Mechanisms of development - 1 Dec 2002
Kunath Melanie, Lüdecke Hermann-Josef, Vortkamp Andrea
Abstract excerpt
The Trps1 gene codes for an atypical member of the GATA type family of transcription factors. Mutations in human TRPS1 lead to the tricho-rhino-phalangeal syndrome types I and III, which are characterized by craniofacial and skeletal abnormalities and disturbed hair development. Correspondingly, during mouse embryonic development strong Trps1 expression is found in the cartilage condensations, the developing...
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