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Article

Isolation, characterization, and expression of the murine Wilms' tumor gene (WT1) during kidney development.

1 Mar 1991

Abstract excerpt

The human Wilms' tumor predisposition gene, WT1, is a Cys-His zinc finger polypeptide which appears to be a transcription factor controlling gene expression during embryonic kidney development. In order to analyze the role of the WT1 gene in nephroblast differentiation, we have isolated the murine homolog of human WT1. An extremely high level of amino acid sequence conservation (greater than 95%) extends...

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Identifiers

PMID: 1671709
DOI: 10.1128/mcb.11.3.1707

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Isolation, characterization, and expression of the murine Wilms' tumor gene (WT1) during kidney development.PMID 1671709Read ↗

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Wilms' tumor gene 1: lessons from the interface between kidney development and cancer.Semantic proximity Read ↗

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Clinical Aspects of WT1 and the Kidney.Semantic proximity Read ↗

Genomic imprinting at the WT1 gene involves a novel coding transcript (AWT1) that shows deregulation in Wilms' tumours.Semantic proximity Read ↗

New insights into the function of the Wilms tumor suppressor geneWT1in podocytesSemantic proximity Read ↗

WT1 and kidney progenitor cellsSemantic proximity Read ↗

Multiple roles for the Wilms' tumour suppressor gene, WT1 in genitourinary development.Semantic proximity Read ↗

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