Article
Testican-1 is dispensable for mouse development.
Matrix biology : journal of the International Society for Matrix Biology - 1 Aug 2006
Röll Sandra, Seul Judith, Paulsson Mats, Hartmann Ursula
Abstract excerpt
Testicans are proteoglycans belonging to the BM-40/SPARC/osteonectin family of extracellular calcium-binding proteins. Testican-1 is strongly expressed in the brain and has been reported to modulate neuronal attachment and matrix metalloproteinase activation. Characterization of the mouse testican-1 gene (Ticn1), consisting of 12 exons out of which exon 3 is alternatively spliced, allowed the construction of a...
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